Journal of critical care
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Journal of critical care · Oct 2018
Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials.
We examined whether patients with acute respiratory distress syndrome (ARDS) lacking risk factors are enrolled in therapeutic trials and assessed their clinical characteristics and outcomes. ⋯ Patients with ARDS without identifiable risk factors are enrolled in therapeutic trials and may have better outcomes, including a higher proportion of rapidly resolving ARDS, than those with risk factors.
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Journal of critical care · Oct 2018
Early enteral nutrition is associated with reduced in-hospital mortality from sepsis in patients with sarcopenia.
To determine whether the association of early enteral nutrition (EEN) with mortality from sepsis differs between patients with and without sarcopenia. ⋯ EEN may be more beneficial in sarcopenic patients.
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Journal of critical care · Oct 2018
Meta AnalysisNon-invasive ventilation in children and adults in low- and low-middle income countries: A systematic review and meta-analysis.
We systematically reviewed the effects of NIV for acute respiratory failure (ARF) in low- and low-middle income countries. ⋯ NIV for ARF in these settings appears to be effective.
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Journal of critical care · Oct 2018
Observational StudyUse of regional citrate anticoagulation for continuous venovenous hemodialysis in critically ill cancer patients with acute kidney injury.
This study aimed to evaluate the safety and efficacy of a regional citrate anticoagulation (RCA) protocol for continuous venovenous hemodialysis (CVVHD) in cancer patients with acute kidney injury (AKI) in the intensive care unit (ICU) setting. ⋯ Filter patency was relatively short and clotting was associated with active cancer disease, genitourinary tumor, lower citrate dose and lower INR.
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Journal of critical care · Oct 2018
Observational StudyLow endocan levels are predictive of Acute Respiratory Distress Syndrome in severe sepsis and septic shock.
Endocan is a circulating proteoglycan measured at high blood levels during severe sepsis, with a likely lung anti-inflammatory function. The aim of this study was to assess whether paradoxically low endocan levels at Intensive Care Unit (ICU) admission could predict Acute Respiratory Distress Syndrome (ARDS) within 72 h in severe septic patients. ⋯ In a cohort of severe septic patients, we observed that low blood levels of endocan at ICU admission were predictive of ARDS at 72 h.