Journal of critical care
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Journal of critical care · Oct 2018
Combined vitamin C, hydrocortisone, and thiamine therapy for patients with severe pneumonia who were admitted to the intensive care unit: Propensity score-based analysis of a before-after cohort study.
To evaluate the efficacy of combined vitamin C, hydrocortisone, and thiamine in patients with severe pneumonia. ⋯ Combined vitamin C, hydrocortisone, and thiamine therapy may benefit patients with severe pneumonia.
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Journal of critical care · Oct 2018
Albumin, a marker for post-operative myocardial damage in cardiac surgery.
Low serum albumin (SA) is a prognostic factor for poor outcome after cardiac surgery. The aim of this study was to estimate the association between pre-operative SA, early post-operative SA and postoperative myocardial injury. ⋯ Post-operative albumin levels were significantly correlated with the amount of postoperative myocardial damage in patients undergoing cardiac surgery independent of typical confounders.
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Journal of critical care · Oct 2018
Hospital variability of postoperative sepsis and sepsis-related mortality after elective coronary artery bypass grafting surgery.
Hospital variability of postoperative sepsis and sepsis-related mortality after elective CABG surgery was not known in Australia. ⋯ Hospital variability of postoperative sepsis, in-hospital mortality and readmission after elective CABG existed between and within public and private hospitals.
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Journal of critical care · Oct 2018
Observational StudySerum total antioxidant capacity during the first week of sepsis and mortality.
Higher circulating total antioxidant capacity (TAC) concentrations have been found in non-survivor than in survivor septic patients at moment of sepsis diagnosis. The objectives of this study were to determine whether serum TAC levels during the first week of sepsis are associated with lipid peroxidation, sepsis severity, and sepsis mortality, and whether could be used as a prognostic biomarker. ⋯ The new findings of our study were that serum TAC levels during the first week of sepsis are associated with lipid peroxidation, sepsis severity, and sepsis mortality, and that could be used as a prognostic biomarker.
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Journal of critical care · Oct 2018
A modified Delphi process to identify, rank and prioritize quality indicators for continuous renal replacement therapy (CRRT) care in critically ill patients.
Continuous renal replacement therapy (CRRT) is a complex and life-sustaining therapy, reserved for our most acutely ill patients, and should be delivered in a safe, consistent and high-quality manner. However valid evidence-based quality indicators (QIs) for CRRT care are lacking. The objective of this study was to develop a prioritized list of QIs for CRRT care that may be used in any CRRT program. ⋯ We developed a prioritized list of 13 QIs for CRRT care. Future work should focus on developing validated benchmarks for these QIs and implementing them into CRRT programs.