Journal of critical care
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Journal of critical care · Apr 2019
ReviewOutcome of invasive mechanical ventilation in cancer patients: Intubate or not to intubate a patient with cancer.
The outcome of cancer patients who undergo mechanical ventilation has been grim. However, it has lately become more promising, creating hesitation when approaching the decision to intubate a cancer patient. Therefore, the main goal was to find some factors that could predict mortality. ⋯ The aforementioned predicting factors could be used when approaching the decision to intubate. When in doubt, we should give the benefit to the patient, proceed to intubate and reevaluate progress daily and in doing so, we would suggest to use the trends in SOFA score and weaning index to assess success or failure of invasive mechanical ventilation.
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Journal of critical care · Apr 2019
ReviewHemodynamic response to β-blockers in severe sepsis and septic shock: A review of current literature.
The administration of β-blockers in patients with sepsis is a trending topic in intensive care medicine since the landmark study by Morelli and colleagues, showing a striking decrease in 28-day mortality compared to standard care. While the available evidence suggests that the use of β-blockers in septic shock is safe, the effects on hemodynamics are controversial. In this paper, we review the effect of β-blockade in septic shock on hemodynamics from animal models to critically ill patients.
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Journal of critical care · Apr 2019
Multicenter Study Observational StudyIncidence and risk factors for alopecia in survivors of critical illness: A multi-centre observational study.
To investigate the incidence, nature and risk factors for patient-reported alopecia in survivors of critical illness. ⋯ Limited research exists examining the incidence, nature and risk factors for patient-reported alopecia in adult survivors of critical illness. The results of this study highlight the need to discuss the potential for alopecia with survivors of critical illness, who had sepsis / septic shock.
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Journal of critical care · Apr 2019
Comparative StudyPrevalence of acute kidney injury after liver transplantation in children: Comparison of the pRIFLE, AKIN, and KDIGO criteria using corrected serum creatinine.
To compare the application of three standardized definitions of acute kidney injury (AKI), using corrected serum creatinine values, in children immediately after liver transplantation. ⋯ There is a good correlation among the three criteria defining AKI in pediatric liver transplant recipients. AKI is highly prevalent in this patient group and confers a worse ICU course.
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Journal of critical care · Apr 2019
Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest.
This study investigates the association between mean arterial pressure (MAP) and renal function after out-of-hospital cardiac arrest (OHCA). ⋯ Low mean MAP during TTM was independently associated with decreased renal function and need of renal replacement therapy in a large cohort of comatose OHCA-patients. Increasing MAP above the recommended 65 mmHg could potentially be renal-protective. This hypothesis should be investigated in prospective trials.