Journal of critical care
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Journal of critical care · Apr 2019
Prognostic nomogram for acute pancreatitis patients: An analysis of publicly electronic healthcare records in intensive care unit.
The mortality rate of severe acute pancreatitis (AP) is 20-30% even after admission to intensive care unit (ICU). Thus we aimed to develop a laboratory-based nomogram to identify AP patients at high risk for mortality. ⋯ The proposed nomogram gives rise to accurately prognostic prediction for critically AP patients admitted to ICU.
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Journal of critical care · Apr 2019
Pharmacokinetics of linezolid in critically ill patients on continuous renal replacement therapy: Influence of residual renal function on PK/PD target attainment.
To assess the pharmacokinetics of linezolid in septic patients undergoing continuous renal replacement therapy (CRRT) and investigate whether residual renal function affects the probability of attaining the pharmacokinetic/pharmacodynamic (PK/PD) target. ⋯ The standard dose (600 mg q12h) ensures a moderately high probability of treatment success in anuric patients when the infection is due to microorganisms with MIC≤2 mg/L; although higher doses increase the probability of treatment success, the safety is compromised. In patients with residual renal function, the standard dose is insufficient, but 900 mg q8h provide higher probability of treatment success without compromising the safety.
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Journal of critical care · Apr 2019
Moral distress is associated with general workplace distress in intensive care unit personnel.
To assess the association between moral distress and general workplace distress in intensive care unit (ICU) personnel. ⋯ Moral distress is associated with general workplace distress in ICU personnel. Interventions that ameliorate either type of distress may also ameliorate the other.
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Journal of critical care · Apr 2019
Bedside chest compression skills: Performance and skills retention in in-hospital trained pediatric providers. A simulation study.
To assess the effects of a real-time feedback device and refresher sessions in acquiring and retaining chest compression skills. ⋯ A real-time visual feedback device improved CC skills with better results in infants. Skills decayed over time despite two refresher sessions with feedback.
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Journal of critical care · Apr 2019
Improving the adoption of optimal venous thromboembolism prophylaxis in critically ill patients: A process evaluation of a complex quality improvement initiative.
This study evaluated a complex initiative to increase evidence-based use of low molecular weight heparin for venous thromboembolism prophylaxis among adult medical-surgical ICU patients. ⋯ The findings of this process evaluation identified implementation strategies that can improve the use of evidence-informed practices, help interpret outcomes in the context of interventions and guide future quality improvement initiatives.