Journal of critical care
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Journal of critical care · Apr 2021
ReviewMajor publications in the critical care pharmacotherapy literature: 2019.
To summarize selected meta-analyses and trials related to critical care pharmacotherapy published in 2019. ⋯ This clinical review and expert opinion provides summary and perspectives of clinical practice impact on influential critical care pharmacotherapy publications in 2019.
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Journal of critical care · Apr 2021
ReviewRelationship between intensive care unit-acquired weakness, fatigability and fatigue: What role for the central nervous system?
To provide a comprehensive review of studies that have investigated fatigue in intensive care unit (ICU) survivors and questions the potential link between intensive care unit-acquired weakness (ICUAW), fatigability and fatigue. We also question whether the central nervous system (CNS) may be the link between these entities. ⋯ Fatigue should be considered and treated in ICU survivors. The causes of fatigue are likely to be specific to the individual. Understanding the role that ICUAW and fatigability may have in fatigue would allow to tailor individual treatment to prevent this persistent symptom and improve quality of life.
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Journal of critical care · Apr 2021
Multicenter StudyIncreasing serum ammonia level is a risk factor for the prognosis of critically ill patients: A multicenter retrospective cohort study.
To assess the association between serum ammonia level upon admission during the initial intensive care unit (ICU) stay and mortality. ⋯ Elevated serum ammonia level in critically ill patients upon admission was an early risk factor for higher ICU and in-hospital mortality.
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Journal of critical care · Apr 2021
Age-related incidence and outcomes of sepsis in California, 2008-2015.
Sepsis remains amongst the most common causes of death worldwide. It has been described as a disease of the elderly, but contemporary data on risk factors and mortality is lacking. ⋯ Age remains an important sepsis risk factor, but other conditions correlated more closely with sepsis-associated death. Patients over 85 years of age suffering from septic shock may have a better chance of survival than previously thought.
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Journal of critical care · Apr 2021
Meta AnalysisSystolic dysfunction as evaluated by tissue Doppler imaging echocardiography and mortality in septic patients: A systematic review and meta-analysis.
Septic induced cardiomyopathy has a wide spectrum of presentation, being associated with systolic and/or diastolic dysfunction. There is currently no evidence of association between left ventricular (LV) systolic dysfunction and mortality in septic patients. ⋯ There is no association between mortality and LV systolic function as evaluated by TDI s' wave in septic patients.