Journal of critical care
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Journal of critical care · Jun 2021
Observational StudyThe prevalence of serotonin syndrome in an intensive care unit: A prospective observational study.
In spite of life-threatening nature of serotonin syndrome (SS), it remains an under-diagnosed condition. The availability of epidemiological data about SS, especially in the ICU setting, may help physicians make early diagnoses and interventions. ⋯ SS is not uncommon in the ICU setting. There is a need to increase awareness among physicians.
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Journal of critical care · Jun 2021
Observational StudyInitial setting of high-flow nasal oxygen post extubation based on mean inspiratory flow during a spontaneous breathing trial.
High flow nasal cannula (HFNC) is commonly used post-extubation in intensive care (ICU). Patients' comfort during HFNC is affected by flow rate. The study aims to describe the relationship between pre-extubation inspiratory flow requirements and the post-extubation flow rates on HFNC that maximises patient's comfort. ⋯ Measuring mean inspiratory flow during an SBT allows for individualised setting of HFNC flow rate immediately post-extubation and achieves the greatest comfort and interface tolerance.
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Journal of critical care · Jun 2021
Effect of early hyperoxemia on the outcome in servere blunt chest trauma: A propensity score-based analysis of a single-center retrospective cohort.
Our study aimed to explore the association between early hyperoxemia of the first 24 h on outcomes in patients with severe blunt chest trauma. ⋯ In our cohort early hyperoxemia during the first 24 h of admission after severe blunt chest trauma was not associated with worse outcome.
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Journal of critical care · Jun 2021
Randomized Controlled TrialAlbumin replacement therapy in immunocompromised patients with sepsis - Secondary analysis of the ALBIOS trial.
The best fluid replacement strategy and the role of albumin in immunocompromised patients with sepsis is unclear. ⋯ Albumin replacement during the ICU stay, as compared with crystalloids alone, did not affect clinical outcomes in a cohort of immunocompromised patients with sepsis.
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Journal of critical care · Jun 2021
Positive fluid balance was associated with mortality in patients with acute-on-chronic liver failure: A cohort study.
We aimed to study the effect of FB in the outcomes of critically-ill patients with cirrhosis. ⋯ FB may be a therapeutic target that helps to improve the outcomes of patients with acute-on-chronic liver failure. This data may inform future clinical trials.