Journal of critical care
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Journal of critical care · Oct 2023
Effects of correction rate for severe hyponatremia in the intensive care unit on patient outcomes.
Limited evidence exists regarding outcomes associated with different correction rates of severe hyponatremia. ⋯ Rapid correction (>8 mEq/L/day) of severe hyponatremia within the first 24 h was associated with lower in-hospital mortality and longer ICU and hospital-free days without an increase in neurological complication. Despite major limitations, including the inability to identify the chronicity of hyponatremia, the results have important implications and warrant prospective studies.
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Journal of critical care · Oct 2023
Visceral obesity measured using computed tomography scans: No significant association with mortality in critically ill patients.
The association between obesity and outcome in critical illness is unclear. Since the amount of visceral adipose tissue(VAT) rather than BMI mediates the health effects of obesity we aimed to investigate the association between visceral obesity, BMI and 90-day mortality in critically ill patients. ⋯ No significant association of visceral obesity and BMI with 90-day mortality was observed in critically ill patients, although obesity and visceral obesity tended to be associated with improved 90-day mortality.
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Journal of critical care · Oct 2023
The impact of timing of initiating invasive mechanical ventilation in COVID-19-related respiratory failure.
Optimal timing of initiating invasive mechanical ventilation (IMV) in coronavirus disease 2019 (COVID-19)-related respiratory failure is unclear. We hypothesized that a strategy of IMV as opposed to continuing high flow oxygen or non-invasive mechanical ventilation each day after reaching a high FiO2 threshold would be associated with worse in-hospital mortality. ⋯ Initiation of IMV on each day after patients reach high FiO2 threshold was associated with higher inpatient mortality after adjusting for time-varying confounders. Remaining on high flow nasal cannula or non-invasive ventilation does not appear to be harmful compared to IMV. Prospective evaluation is needed.
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Journal of critical care · Oct 2023
Psychiatric patients' intensive care admission characteristics, weaning from mechanical ventilation and sedative drug use: A single center retrospective case-control study.
To describe the characteristics, treatment and outcome, in particular weaning from mechanical ventilation (MV), of critically ill Patients with prior psychiatric conditions (PPC). ⋯ Critically ill PPC had higher mortality rates than their matched counterparts. They also had higher MV rates and were more difficult to wean.