Journal of critical care
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Journal of critical care · Apr 2023
Identifying high-risk phenotypes and associated harms of delayed time-to-antibiotics in patients with ICU onset sepsis: A retrospective cohort study.
To identify phenotypes of Intensive Care Unit (ICU) onset sepsis and its associated harms of delayed time-to-antibiotics. ⋯ Septic patients with respiratory or cardiovascular dysfunction were associated with harms of delayed time-to-antibiotics.
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Acute intracerebral hemorrhage is a medical emergency with high mortality and morbidity. Neuroimaging has a fundamental role in the etiological diagnosis, patients monitoring and in the risk stratification of hematoma expansion and poor outcome. ⋯ Prevention of hematoma expansion is the main goal of these therapies and their efficacy is strongly time-dependent with a narrow time window. This review provides an update on the etiological diagnostic workup, acute treatment and prognosis of intracerebral hemorrhage.
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Journal of critical care · Apr 2023
Letter Observational StudyCoagulopathy correlates with muscle titin injury in critically ill patients.
We hypothesized that coagulopathy independently contributes to muscle injury focusing to titin fragmentation, and investigated their correlations. ⋯ Coagulopathy correlated with muscle titin fragmentation, as an independent risk factor.