Journal of critical care
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Journal of critical care · Aug 2018
Multicenter StudyLate organ failures in patients with prolonged intensive care unit stays.
The purpose of this study was to characterize the organ failures that develop among patients with prolonged ICU stays, defined as those who spent a minimum of 14 days in an ICU. ⋯ Strategies aiming to reduce the development of new late organ failures may be a novel target for preventing persistent critical illness.
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Journal of critical care · Aug 2018
Multicenter Study Observational StudyOxygen management in mechanically ventilated patients: A multicenter prospective observational study.
To observe arterial oxygen in relation to fraction of inspired oxygen (FIO2) during mechanical ventilation (MV). ⋯ In our multicenter prospective study, we found that hyperoxemia was common and that hyperoxemia was not corrected.
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Journal of critical care · Aug 2018
Multicenter Study Observational StudyThe systemic inflammatory response syndrome criteria and their differential association with mortality.
Despite the recent Sepsis-3 consensus, the Systemic Inflammatory Response Syndrome (SIRS) criteria continue to be assessed and recommended. Such use implies equivalence and interchangeability of criteria. Thus, we aimed to test whether such criteria are indeed equivalent and interchangeable. ⋯ Different individual and combinations of SIRS criteria were associated with marked differences in hospital mortality. These differences remained unchanged after adjustment and over time and imply that individual SIRS criteria are not equivalent or interchangeable.
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Journal of critical care · Jun 2018
Multicenter Study Observational StudyEarly glycemia and mortality in critically ill septic patients: Interaction with insulin-treated diabetes.
To investigate the relationship between dysglycemia and hospital mortality in patients with and without a preadmission diagnosis of insulin treated diabetes mellitus (ITDM). ⋯ Septic patients with a pre-existing diagnosis of ITDM show a different relationship between hospital mortality and highest glucose levels and glycemic variability in the first 24 h than those without ITDM. These findings provide a rationale for an ITDM-specific approach to the management of dysglycemia.