Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Clinical Trial
Intra-articular tenoxicam improves postoperative analgesia in knee arthroscopy.
Non Steroidal Anti-inflammatory drugs have a well documented benefit in the relief of postoperative pain. This study was designed to compare the analgesic effect of intra-articular tenoxicam 20 mg with intravenous tenoxicam on postoperative pain in 88 patients undergoing day case knee arthroscopy. ⋯ Intra-articular tenoxicam provides superior postoperative analgesia and reduces postoperative analgesic requirements compared with i.v. tenoxicam in patients undergoing day case knee arthroscopy.
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Randomized Controlled Trial Clinical Trial
Low dose axillary block by targeted injections of the terminal nerves.
To compare anesthetic time, success rate and adverse effects of axillary block by single or multiple injections of local anesthetic. ⋯ Small targeted injections of MEPE reduce total anesthetic time, give better spread of analgesia in the hand and forearm, and may be safer than a single large injection.
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Randomized Controlled Trial Clinical Trial
Covering the head and face maintains intraoperative core temperature.
To determine the effect of covering the patient's head and face on the prevention of intraoperative hypothermia (<35.5 degrees C). ⋯ Covering the patient's head and face maintains intraoperative core temperature.
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The auditory evoked potential (AEP) has been proposed as a method to determine depth of anesthesia, as AEPs are generated in the thalamus and cerebral cortex. Because general anesthesia, in part, relies on anesthetic action in the spinal cord, we hypothesized that isoflurane would have indirect depressant effects on the AEP because of its action in the spinal cord. ⋯ Isoflurane action in the spinal cord indirectly alters the AEP, however, the effect is small. These data suggest that isoflurane can depress the transmission of afferent information from the spinal cord to thalamus, midbrain and cerebral cortex.
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Treatment with angiotensin-converting enzyme (ACE) inhibitors affects the autoregulation of renal blood flow and glomerular filtration and provides renal protective effects. The purpose of this case-control study was to investigate the effects of chronic ACE inhibition on perioperative renal hemodynamics and function. ⋯ Long term treatment with ACE inhibitors does not influence the perioperative changes in renal hemodynamics and function. During cardiopulmonary bypass, a transient impairment in solute reabsorption is associated with renal release of vasodilatory mediators (nitric oxide and prostacyclin).