Canadian journal of anaesthesia = Journal canadien d'anesthésie
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To determine whether the compromised intestinal villus blood flow in a rat model of endotoxemia could be improved by continuous infusion of the phosphodiesterase (PDE) inhibitor milrinone. ⋯ Our results indicate that milrinone has some beneficial microcirculatory effects during endotoxemia. Although it contributed to systemic hypotension, it attenuated intestinal mucosal hypoperfusion.
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Randomized Controlled Trial Comparative Study Clinical Trial
Hemodynamics, intramucosal pH and regulators of circulation during perioperative epidural analgesia.
To evaluate the effects of perioperative epidural analgesia on hemodynamics, splanchnic perfusion and regulators of circulation. ⋯ Perioperatively administrated epidural bupivacaine has no beneficially effects on hemodynamics, pHi or release of regulators of circulation.
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Randomized Controlled Trial Clinical Trial
Gastric distension and ventilation during laparoscopic cholecystectomy: LMA-Classic vs. tracheal intubation.
The standard laryngeal mask airway LMA-Classic was designed as an alternative to the endotracheal tube (ETT) or the face mask for use with either spontaneous or positive pressure ventilation. Positive pressure ventilation may exploit leaks around the LMA cuff, leading to gastric distension and/or inadequate ventilation. We compared gastric distension and ventilation parameters with LMA vs ETT during laparoscopic cholecystectomy. ⋯ Positive pressure ventilation with a correctly placed LMA-Classic of appropriate size permits adequate pulmonary ventilation. Gastric distension occurs with equal frequency with either airway device.
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Randomized Controlled Trial Clinical Trial
Oral clonidine premedication reduces propofol requirement for laryngeal mask airway insertion.
To determine the effect of oral clonidine premedication on propofol requirement (ED(50)) for the insertion of the laryngeal mask airway (LMA) in healthy patients undergoing abdominal hysterectomy. ⋯ Oral clonidine premedication reduces propofol requirement for LMA insertion.