Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Comparative Study Controlled Clinical Trial
Carbetocin at elective Cesarean delivery: a sequential allocation trial to determine the minimum effective dose.
The ED90 of carbetocin is approximately 15 mcg after elective cesarean section.
pearl -
Comparative Study
Estimation of equivalent threshold currents using different pulse widths for the epidural stimulation test in a porcine model.
The epidural stimulation test can help detect if a catheter is correctly positioned in the epidural space. Previous studies showed that a current of up to 16 mA was required to elicit a motor response, but few peripheral nerve stimulators can produce a current this high. Manipulating pulse width can produce a positive response at a lower current. To clarify the effects of pulse width on the epidural stimulation test, we performed a single-blinded study in a porcine model to estimate the equivalent current needed at varying pulse widths. ⋯ In situations where different pulse widths are needed, the nomograms presented here may be useful to estimate the equivalent threshold current which is required to elicit a motor response according to previously published criteria for epidural stimulation tests.