Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Case Reports
Reversal of a rocuronium-induced grade IV anaphylaxis via early injection of a large dose of sugammadex.
To report rapid recovery from grade IV rocuronium-induced anaphylaxis with a large dose of sugammadex administered early after the onset of symptoms. ⋯ Very early administration of a large dose of sugammadex may be an effective treatment for rocuronium-induced anaphylaxis.
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Controlled Clinical Trial
Use of near infrared spectroscopy to detect impaired tissue oxygen saturation in patients with complex regional pain syndrome type 1.
Deep tissue hypoxia has been hypothesized in the pathogenesis of complex regional pain syndrome type 1 (CRPS 1) for some patients. The purpose of this study was to determine if near-infrared spectroscopy (NIRS) could detect differences in deep tissue oxygen saturation (StO2) and microcirculatory function in the hands of patients with CRPS 1. ⋯ Hands of patients affected by CRPS 1 of the upper limb showed significantly lower StO2 compared with their unaffected contralateral hand as well as the hands of control subjects. This trial was registered at: ClinicalTrials.gov: NCT01586377.