Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Increased mean platelet volume (MPV) may indicate platelet activation, platelet aggregation, and a resulting prothrombotic state. Such changes in the postoperative period have been associated with organ injury and adverse outcomes. We hypothesized that changes in MPV after cardiac surgery are associated with both a higher risk of acute kidney injury (AKI) and mortality. ⋯ Increased MPV change in the postoperative period was associated with both increased risk and severity of AKI, but not mortality.