Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Clinical Trial
Intraoperative phlebotomies and bleeding in liver transplantation: a historical cohort study and causal analysis.
Liver transplantation is associated with major bleeding and red blood cell (RBC) transfusions. No well-designed causal analysis on interventions used to reduce transfusions, such as an intraoperative phlebotomy, has been conducted in this population. ⋯ gov (NCT04826666); registered 1 April 2021.
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Editorial Comment
Observational studies: a perpetual quest for a signal among the noise.
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Randomized Controlled Trial
Effects of intraoperative dexmedetomidine infusion on renal function in elective living donor kidney transplantation: a randomized controlled trial.
Ischemia-reperfusion injury is inevitable during donor organ harvest and recipient allograft reperfusion in kidney transplantation, and affects graft outcomes. Dexmedetomidine, an α2-adrenoreceptor agonist, has renoprotective effects against ischemia-reperfusion injury. We investigated the effects of intraoperative dexmedetomidine infusion on renal function and the development of delayed graft function after elective living donor kidney transplantation in a randomized controlled trial. ⋯ gov (NCT03327389); registered 31 October 2017.
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Observational Study
Competence of anesthesiology residents following a longitudinal point-of-care ultrasound curriculum.
Point-of-care ultrasound (POCUS) facilitates diagnostic, procedural, and resuscitative applications in anesthesiology. Structured POCUS curricula improve learner satisfaction, test scores, and clinical management, but the learning curve towards competency and retention of skills over time remain unknown. ⋯ Our study shows that anesthesiology residents can achieve competence in rescue echo and lung ultrasound through participation in a structured, longitudinal POCUS curriculum, and outlines the learning curve for progression towards competency.