Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
Ketamine sedation in the intensive care unit: a survey of Canadian intensivists.
We sought to understand the beliefs and practices of Canadian intensivists regarding their use of ketamine as a sedative in critically ill patients and to gauge their interest in a randomized controlled trial (RCT) examining its use in the intensive care unit (ICU). ⋯ This survey of Canadian intensivists illustrates that use of ketamine as a continuous infusion for sedation is limited, and is at least partly driven by concerns of adverse psychotropic effects. Canadian physicians endorse the need for a trial investigating the safety and efficacy of ketamine as a sedative for critically ill patients.
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Randomized Controlled Trial
Comparing leak pressure of LMA® ProSeal™ versus i-gel® at head rotation: a randomized controlled trial.
The effect of head rotation on supraglottic airway (SGA) oropharyngeal leak pressure (OPLP) has not been well elucidated. The aim of this study was to help clarify which SGA device provides higher OPLP at head-rotated position. ⋯ The LMA ProSeal provides higher OPLP than the i-gel at a 60° head-rotated position under general anesthesia.
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Randomized Controlled Trial Observational Study
Accuracy of the Nova StatStrip® glucometer in patients undergoing major abdominal surgery: an observational study.
While the Nova StatStrip® Glucose Hospital Meter System (Nova Biomedical, Waltham, MA, USA) is approved for point-of-care testing (POCT) in critically ill patients, its use during major abdominal surgery has not been evaluated. The purpose of this study was to assess the accuracy of the Nova StatStrip glucometer in patients undergoing major hepatobiliary procedures using the Parkes error grid (ISO15197:2013) and criteria defined by the Clinical and Laboratory Standards Institute (CLSI) POCT12-A3 guideline. ⋯ ClinicalTrials.gov (NCT01528189); registered 7 February 2012.
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Randomized Controlled Trial
A model to predict level of adherence to prehabilitation in older adults with frailty having cancer surgery.
Preoperative exercise could improve postoperative outcomes for people with frailty; however, little is known about how to predict older people's adherence to exercise before surgery (i.e., prehabilitation) programs. Our objective was to derive and validate a model to predict prehabilitation adherence in older adults living with frailty before cancer surgery. ⋯ A prespecified multivariable model may help to explain a modest degree of variation in prehabilitation adherence in older people with frailty. While this model is an important step toward personalizing prehabilitation support, this study was limited by a small sample size and future research is needed to better understand personalized prediction of prehabilitation adherence in older people with frailty.
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Letter Randomized Controlled Trial
A randomized controlled trial of passive leg raise to facilitate pediatric peripheral intravenous access.