Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Historical Article
From the Journal archives: A harbinger of modern anesthesia.
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Randomized Controlled Trial
Prophylactic glycopyrrolate reduces hypotensive responses in elderly patients during spinal anesthesia: a randomized controlled trial.
Hypotension during spinal anesthesia is a serious complication in elderly patients. We evaluated the effect of glycopyrrolate on hypotensive responses in elderly patients undergoing spinal anesthesia. ⋯ Prophylactic intramuscular glycopyrrolate reduced the occurrence and severity of hypotensive responses, the requirement for ephedrine, and the incidence of nausea and vomiting in elderly patients undergoing spinal anesthesia. The trial was registered at the Clinical Research Information Service, Republic of Korea (KCT0000556).
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Clinical Trial Observational Study
Untreated preoperative depression is not associated with postoperative arrhythmias in CABG patients.
The mechanism by which depression affects postoperative outcome may involve arrhythmias. The purpose of this study was to evaluate whether untreated depression is associated with an increased incidence of postoperative arrhythmias in patients undergoing coronary artery bypass graft surgery (CABG). ⋯ Preoperative untreated depression is not related to postoperative arrhythmia in the early postoperative period in patients undergoing elective CABG. This trial was registered at clinicaltrials.gov (number: NCT00622024).