Neurology India
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Posterior reversible encephalopathy syndrome is characterized by acute headache, visual impairment, seizures, and altered mental status; neuroimaging may show cerebral edema affecting the parietal and occipital lobes of the brain. The objective of this article is to review the current understanding of posterior reversible encephalopathy syndrome in eclampsia. Literature was searched from PubMed, Scopus, and Google Scholar databases. ⋯ Some survivors may have permanent vision loss and other disabling sequelae. In conclusion, posterior reversible encephalopathy is a devastating complication of eclampsia. Early recognition helps in preventing some of its devastating sequelae.
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Endocrinal insufficiency caused by vasculotoxic snake envenomation is under-recognized and is mostly confined to a specific geographic area. We conducted a prospective study to determine the prevalence and pattern of pituitary-target gland insufficiencies caused by snake envenomation. ⋯ Acute asymptomatic and chronic symptomatic or asymptomatic hypopituitarism are important sequelae of viper bite in a small proportion of patients and can occur in the presence of normal pituitary imaging. Routine prospective pituitary hormone screening should be done in all patients within the first 6 months of envenomation by the vasculotoxic snakebite as chronic pituitary dysfunction can often occur in these patients.
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Even after making allowance for an unprecedented hype, it is an undeniable fact that, in the coming decade, deployment of Artificial Intelligence (AI) will cause a paradigm shift in the delivery of healthcare. This paper will review the practical utility of AI in neurosciences from a clinician's perspective. Steering clear of the complex, technical, computational jargon, the authors will critically review the exponential development in this area from a clinical standpoint. ⋯ AI requires a thorough and systematic evaluation, prior to integration in the clinical care. Like other disruptive technologies in the past, its potential for causing a great impact should not be underestimated. A scenario in which medical information, gathered at the point of care, is analyzed using sophisticated machine algorithms to provide real-time actionable analytics seems to be within touching distance.
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Congenital disorders of the craniovertebral junction (CVJ) include a wide range of conditions, such as Chiari malformation (CM), basilar Invagination (BI), and atlantoaxial dislocation (AAD). The objective of this paper is to critically review the literature related to the management of congenital CVJ disorders focusing on: the significant developments in the past (from anterior open ventral decompression to modern CVJ realignment); the diagnosis of CVJ instability; the role of atlantoaxial fixation without posterior fossa decompression in patients with tonsillar herniation and no evidence of CVJ instability; use of C1-2 inter-articular spacers and use of C1-2 interarticular spacers with intra-operative manipulations to correct BI with AAD along with its deformity. ⋯ We present a critical review of important new concepts involved in the surgical treatment of CVJ congenital disease.