Critical care medicine
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Critical care medicine · Oct 1991
Randomized Controlled Trial Comparative Study Clinical TrialReduction of colonization and infection rate during pediatric intensive care by selective decontamination of the digestive tract.
To compare the effects of two different antibiotic regimes on the colonization and infection rates of critically ill pediatric patients. ⋯ Selective oropharyngeal and gastrointestinal decontamination combined with systemic cefotaxime application allows for a significant reduction of the colonization rate with Gram-negative bacteria and yeasts in critically ill pediatric patients undergoing prolonged intensive care. In addition, it significantly reduces the Gram-negative infection rate of the respiratory system. However, this therapeutic approach does not alter ICU length of stay or mortality rate.
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Critical care medicine · Oct 1991
Comparative StudyEffect of associated injuries and blood volume replacement on death, rehabilitation needs, and disability in blunt traumatic brain injury.
To examine the effects of associated injuries on death, disability, rehabilitation needs, and cost in patients with blunt traumatic brain injury. ⋯ In blunt traumatic brain injury, the addition of major visceral or extremity injuries, with need for blood replacement or shock, increases the risk of death, the need for rehabilitation, and the costs of disability.
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Critical care medicine · Oct 1991
Comparative StudyMeasurement of alveolar ventilation and changes in deadspace by indirect calorimetry during mechanical ventilation: a laboratory and clinical validation.
To validate the assessment of changes in alveolar ventilation and deadspace by indirect calorimetry. ⋯ Changes in alveolar ventilation and deadspace can be accurately measured by combined use of indirect calorimetry and end-tidal CO2 analysis.