Critical care medicine
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Critical care medicine · Dec 1999
Comment Letter Biography Historical ArticleAnother European view: the origin of pulmonary artery catheterization.
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Critical care medicine · Dec 1999
Randomized Controlled Trial Multicenter Study Clinical TrialRisk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group.
To evaluate the incidence and risk factors for clinically important upper gastrointestinal bleeding in critically ill patients requiring mechanical ventilation. ⋯ In critically ill ventilated patients, renal failure was independently associated with an increased risk of clinically important gastrointestinal bleeding, whereas enteral nutrition and stress ulcer prophylaxis with ranitidine conferred significantly lower bleeding rates.
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Critical care medicine · Dec 1999
Multicenter Study Clinical Trial Controlled Clinical TrialLong-term follow-up of survivors of acute lung injury: lack of effect of a ventilation strategy to prevent barotrauma.
To determine the effect of a ventilation strategy to prevent barotrauma on long-term outcome in survivors of acute lung injury. ⋯ We found that 1-2 yrs after the onset of their illness, survivors of acute lung injury have reductions in quality of life and exercise tolerance which are similar to patients with chronic diseases. We were unable to show that a limited ventilation strategy improves either long-term pulmonary function or quality of life in survivors of acute lung injury.
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Critical care medicine · Dec 1999
Meta AnalysisImmunonutrition in the critically ill: a systematic review of clinical outcome.
To perform a meta-analysis addressing whether enteral nutrition with immune-enhancing feeds benefits critically ill patients after trauma, sepsis, or major surgery. ⋯ The benefits of enteral immunonutrition were most pronounced in surgical patients, although they were present in all groups. The reduction in hospital length of stay and infections has resource implications.
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Critical care medicine · Dec 1999
Randomized Controlled Trial Comparative Study Clinical TrialParalysis in the critically ill: intermittent bolus pancuronium compared with continuous infusion.
To compare recovery times from neuromuscular blockade between two groups of critically ill patients in whom pancuronium was administered by continuous infusion or intermittent bolus injection. To compare the mean pancuronium requirements (milligrams per kilogram per hour) and to assess the incidence of prolonged recovery times (>12 hrs) and residual muscle weakness. ⋯ Our study suggests that recovery time after paralysis with continuous infusion is faster than that after intermittent bolus injection. Although more pancuronium was administered in the continuous-infusion group, recovery time was not prolonged as a consequence. It is uncertain whether pancuronium given by infusion increases the risk of persistent muscle weakness.