Critical care medicine
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Critical care medicine · Jun 2000
The role of tumor necrosis factor in the development of multiple organ failure in a murine model.
To elucidate the role of tumor necrosis factor (TNF) in the development of multiple organ dysfunction syndrome (MODS) after zymosan-induced peritonitis in mice. ⋯ Organ-derived TNF-alpha plays a crucial role in the development of MODS in this murine model.