Critical care medicine
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Critical care medicine · Sep 2013
Airway Fungal Colonization Compromises the Immune System Allowing Bacterial Pneumonia to Prevail.
To study the correlation between fungal colonization and bacterial pneumonia and to test the effect of antifungal treatments on the development of bacterial pneumonia in colonized rats. ⋯ C. albicans airway colonization elicited a Th1-Th17 immune response that favored the development of bacterial pneumonia via the inhibition of bacterial phagocytosis by alveolar macrophages. Antifungal treatment decreased the risk of bacterial pneumonia in colonized rats.
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Critical care medicine · Sep 2013
Editorial CommentA new purpose for proportional assist ventilation?*.