Critical care medicine
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Critical care medicine · Dec 2014
Review Meta AnalysisTidal Volume and Mortality in Mechanically Ventilated Children: A Systematic Review and Meta-Analysis of Observational Studies.
To determine whether tidal volume is associated with mortality in critically ill, mechanically ventilated children. ⋯ A relationship between tidal volume and mortality in mechanically ventilated children could not be identified, irrespective of the severity of disease. The significant heterogeneity observed in the pooled analyses necessitates future studies in well-defined patient populations to understand the effects of tidal volume on patient outcome.