Critical care medicine
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Critical care medicine · Oct 2018
Randomized Controlled Trial Observational StudyValidation and Clinical Evaluation of a Method for Double-Blinded Blood Pressure Target Investigation in Intensive Care Medicine.
No double-blinded clinical trials have investigated optimal mean arterial pressure targets in the ICU. The aim of this study was to develop and validate a method for blinded investigation of mean arterial pressure targets in patients monitored with arterial catheter in the ICU. ⋯ The present method is feasible and robust and provides a platform for double-blinded comparison of mean arterial pressure targets in critically ill patients.