Critical care medicine
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Critical care medicine · Nov 2020
Characteristics, Hospital Course, and Outcomes of Patients Requiring Prolonged Acute Versus Short-Term Mechanical Ventilation in the United States, 2014-2018.
Most patients requiring mechanical ventilation only require it for a short term (< 4 d of mechanical ventilation). Those undergoing prolonged acute mechanical ventilation (≥ 4 d mechanical ventilation) represent a select cohort who face significant morbidity, mortality, and resource utilization. Using administrative codes, we identified prolonged acute mechanical ventilation and short-term mechanical ventilation patients and compared their baseline characteristics, hospital events, and hospital outcomes. ⋯ Over one-third of all hospitalized patients on mechanical ventilation require it for greater than or equal to 4 days. Prolonged acute mechanical ventilation patients exhibit a higher burden of both chronic and acute illness and experience higher rates than those on short-term mechanical ventilation of hospital-acquired complications and worse clinical and economic outcomes.
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Critical care medicine · Nov 2020
Practices in Triage and Transfer of Critically Ill Patients: A Qualitative Systematic Review of Selection Criteria.
To identify and appraise articles describing criteria used to prioritize or withhold a critical care admission. ⋯ This systematic review identified 200 criteria classified within four themes that may be included when devising triage programs including the coronavirus disease 2019 pandemic. We identified significant knowledge gaps where research would assist in improving existing triage criteria and guidelines, aiming to decrease arbitrary decisions and variability.
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Critical care medicine · Nov 2020
Critical Care for Coronavirus Disease 2019: Perspectives From the PICU to the Medical ICU.
To describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic. ⋯ In the coronavirus disease 2019 pandemic, PICU physicians are well poised to care for adult patients in a surge capacity, and bring a unique perspective to the experience.
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Critical care medicine · Nov 2020
Obesity and the Risk of Intubation or Death in Patients With Coronavirus Disease 2019.
To characterize the impact of obesity on disease severity in patients with coronavirus disease 2019. ⋯ Among consecutive patients hospitalized with coronavirus disease 2019, obesity was an independent risk factor for intubation or death.
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Critical care medicine · Nov 2020
Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study).
Bloodstream infection is an important cause of death worldwide. The main objective of this study was to identify genetic loci linked to risk of contracting a bloodstream infection. ⋯ Variations in the TLR10/1/6 locus appear to be linked with the risk of contracting a bloodstream infection.