Critical care medicine
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Critical care medicine · Jan 1997
Retracted PublicationDoes age influence circulating adhesion molecules in the critically ill?
Soluble adhesion molecules are regarded to be markers of inflammation, endothelial activation, or damage. The influence of age on plasma concentrations of circulating adhesion molecules should be serially studied in critically ill intensive care patients. ⋯ The higher plasma concentrations of the measured adhesion molecules in elderly critically ill patients indicate that elderly patients are more prone than younger patients to a more pronounced activation or even damage of the endothelium. Further work needs to be done to determine the prognostic importance and to define the role of soluble adhesion molecules, particularly in the elderly critically ill patient.
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Critical care medicine · Jun 1996
Randomized Controlled Trial Clinical Trial Retracted PublicationInfluence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients.
To determine the influence of pentoxifylline on endothelial-associated coagulation. ⋯ Continuous intravenous administration of pentoxifylline for 5 days beneficially influenced the thrombomodulin/protein C/protein S system in both the trauma and septic patients.
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Critical care medicine · Mar 1996
Review Randomized Controlled Trial Clinical Trial Retracted PublicationInfluence of different volume therapies and pentoxifylline infusion on circulating soluble adhesion molecules in critically ill patients.
To study the influence of long-term volume therapy with different solutions and continuous administration of pentoxifylline on plasma concentrations of circulating adhesion molecules. ⋯ Sepsis is associated with markedly increased plasma concentrations of adhesion molecules, indicating endothelial activation or damage. By long-term volume therapy with hydroxyethal starch solution, these concentrations remained unchanged or even decreased, whereas in patients in whom human albumin was infused or pentoxifylline was given continuously, plasma concentration of soluble adhesion molecules further increased.
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Critical care medicine · Dec 1994
Comparative Study Retracted PublicationIs continuous cardiac output measurement using thermodilution reliable in the critically ill patient?
Evaluation of continuous cardiac output monitoring based on the thermodilution technique in the critically ill. ⋯ Continuous monitoring of cardiac output using a modified pulmonary artery catheter with a heated filament has proven to be accurate and precise in the critically ill patient when compared with the "standard" intermittent bolus thermodilution technique. The continuous monitoring technique enhances our armamentarium for more intensive monitoring of these patients under a variety of circumstances.
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Critical care medicine · Jul 1994
Comparative Study Retracted PublicationContinuous hemofiltration and platelet function in critically ill patients.
To evaluate platelet function in patients undergoing continuous pump-driven veno-venous hemofiltration. ⋯ Continuous pump-driven veno-venous hemofiltration significantly changed platelet aggregability, which became obvious 2 to 3 days after the start of hemofiltration.