Alimentary pharmacology & therapeutics
The most recent articles from:
Aliment. Pharmacol. Ther.
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Aliment. Pharmacol. Ther. · Jun 2020
Meta AnalysisSystematic review with meta-analysis: the efficacy of tranexamic acid in upper gastrointestinal bleeding.
Upper gastrointestinal bleeding is a common medical emergency associated with substantial mortality. Tranexamic acid may be effective for reducing mortality in upper gastrointestinal bleeding. ⋯ Moderate-quality evidence shows that tranexamic acid is superior to placebo for the reduction in mortality in patients with upper gastrointestinal bleeding. While our findings lend further support to the use of tranexamic acid for treating patients with upper gastrointestinal bleeding, additional higher-quality trials are needed.