Journal of veterinary internal medicine
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J. Vet. Intern. Med. · May 2011
Effect of experimental endotoxemia on thrombelastography parameters, secondary and tertiary hemostasis in dogs.
Thrombelastography (TEG) and indicators of secondary and tertiary hemostasis might be altered in dogs with endotoxemia. ⋯ D-Dimers are the earliest indicator for endotoxemia-associated coagulation abnormalities followed by decreased protein C concentration. APC-ratio and TEG were not good screening variables.
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Coagulopathies in horses with gastrointestinal disease are frequently identified and associated with morbidity and fatality. ⋯ TEG identifies changes in coagulation and fibrinolysis associated with lesion type, SIRS, morbidity, and fatality in horses with gastrointestinal disease.
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J. Vet. Intern. Med. · Jan 2011
Multicenter StudyBiomarkers of brain injury in foals with hypoxic-ischemic encephalopathy.
Neonatal hypoxic-ischemic encephalopathy (NHIE) is a disease affecting newborn foals for which there is no antemortem diagnostic test. ⋯ UCHL1 has potential as a marker of brain injury in foals with NHIE.
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Treating cancer with drugs is an ancient art, but it is from discoveries made during and after the Second World War that real clinical success with cancer chemotherapy has occurred. Human and veterinary cancer chemotherapy have coevolved in the context of fascinating historical, political, and scientific events created by equally fascinating individuals.
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J. Vet. Intern. Med. · Sep 2010
Intravenous administration of azumolene to reverse malignant hyperthermia in swine.
The efficacy of intravenous (IV) administration of azumolene (Az), an analogue 30-fold more soluble than dantrolene, on pigs susceptible to malignant hyperthermia (MH) is incompletely understood. ⋯ Az represents a possible substitute for dantrolene to reverse MH crisis in susceptible pigs.