Paediatric and perinatal epidemiology
-
Paediatr Perinat Epidemiol · May 2014
Survival at the threshold of viability: a nationwide survey of the opinions and attitudes of physicians in a developing country.
To explore physicians' opinions and attitudes regarding resuscitation of extremely premature infants (EPIs) in a developing country with suboptimal resources. ⋯ The majority of surveyed physicians consider infants at gestational age less than or equal to 25 weeks gestation or 800 g at birth as non-viable, and therefore would not attempt their resuscitation. Factors influencing threshold of viability in developing countries need to be addressed and explored further.
-
Paediatr Perinat Epidemiol · Mar 2014
Race/ethnicity, educational attainment, and pregnancy complications in New York City women with pre-existing diabetes.
More women are entering pregnancy with pre-existing diabetes. Disease severity, glycaemic control, and predictors of pregnancy complications may differ by race/ethnicity or educational attainment, leading to differences in adverse pregnancy outcomes. ⋯ Non-Hispanic black, Hispanic, and South Asian women with pre-existing diabetes may benefit from targeted interventions to improve pregnancy outcomes.
-
Paediatr Perinat Epidemiol · Jan 2014
Variation by diagnostic subtype in risk for autism spectrum disorders associated with maternal parity among Finnish births.
Associations between maternal parity and outcomes in offspring may provide evidence for involvement of prenatal exposures. The objective of this study was to determine whether risk for autism spectrum disorders (ASD) is associated with maternal parity. ⋯ Differences in patterns of association between maternal parity and ASD subtypes may indicate varying contributions of specific environmental factors to risk; however, differences in diagnosis or in treatment seeking for childhood behavioural problems cannot be ruled out, particularly for higher functioning cases.
-
Paediatr Perinat Epidemiol · Jan 2014
Predicting risk of spontaneous preterm delivery in women with a singleton pregnancy.
Prediction of a woman's risk of a spontaneous preterm delivery (PTD) is a core challenge and an unresolved problem in today's obstetric practice. The objective of this study was to develop prediction models for spontaneous PTD (<37 weeks). ⋯ Spontaneous PTD is difficult to predict in multiparous women and nearly impossible in primiparous, by using this statistical method in a large and unselected sample. However, adding clinical data (like cervical length) may in the future further improve its predictive performance.
-
Paediatr Perinat Epidemiol · Nov 2013
Randomized Controlled Trial Multicenter StudyA randomised trial to evaluate the effects of low-dose aspirin in gestation and reproduction: design and baseline characteristics.
Low-dose aspirin (LDA) has been proposed to improve pregnancy outcomes in couples experiencing recurrent pregnancy loss. However, results from studies of LDA on pregnancy outcomes have been inconsistent, perhaps because most studies evaluated LDA-initiated post-conception. The purpose of the Effects of Aspirin in Gestation and Reproduction (EAGeR) trial was to determine whether preconception-initiated LDA improves livebirth rates in women with one to two prior losses. ⋯ We describe the study design, recruitment, data collection, and baseline characteristics of participants enrolled in EAGeR, which aimed to determine the effect of LDA on livebirth and other pregnancy outcomes in these women.