British journal of neurosurgery
-
Traumatic brain injury (TBI) is the commonest cause of death and disability in young adults living in industrialised countries. Recently, several studies have shown that hypopituitarism is a common complication of head trauma, with a prevalence of at least 25% among patients who were studied months or years following injury. ⋯ This article discusses the published reports on neuroendocrine dysfunction in TBI patients and the natural history of this disorder. The potential impact of posttraumatic hypopituitarism on recovery and rehabilitation after injury will also be examined, as well as the need for the identification, and appropriate and timely management of hormone deficiencies in order to reduce morbidity, aid recovery, and avoid the long-term complications of pituitary failure.
-
Biography Historical Article
Hugh Cairns and the origin of British neurosurgery.
Sir Hugh Cairns, the first Nuffield Professor of Surgery in Oxford and consultant neurosurgeon to the Royal Army Medical Corps during World War II, was a leader in helping to establish neurosurgery as a speciality in Britain. After learning the craft from Dr Harvey Cushing in Boston, Cairns fought against the general surgical orthodoxy in London to establish the first specialised neurosurgical unit in a teaching hospital. We review his early life, training with Cushing, his inspiring character and administrative prowess which not only helped to win the battle for neurosurgery in London but also helped to establish the Oxford Clinical School and to save thousands of lives during the Second World War.
-
Recently published data from the International Subarachnoid Aneurysm Trial (ISAT) shows that for patients enrolled in the trial there is a 7.4% reduction in the incidence of death or dependency at 1 year if they undergo coiling, rather than clipping. Furthermore, extrapolation of longer-term follow-up data for patient mortality appears to suggest that this advantage will be maintained in the longer term. ⋯ Treatment of aneurysms is a continually evolving field and there is currently no other major source of information concerning management of aneurysms. For these reasons the authors recommend the instigation of a national aneurysm registry to prospectively collect data.