European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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Eur J Cardiothorac Surg · Nov 2003
Randomized Controlled Trial Clinical TrialProphylactic milrinone during OPCAB of posterior vessels: implication in angina patients taking beta-blockers.
To determine whether a phosphodiesterase type 3 inhibitor can improve hemodynamics during off-pump coronary artery bypass grafting (OPCAB) of posterior vessels in patients on beta(1)-adrenoreceptor blockers. ⋯ Prophylactic milrinone improves CI, SVI and SvO(2) reducing the need for high doses of dopamine during OM anastomosis in patients taking atenolol. Therefore, it can be used as an alternative to dopamine improving hemodynamics and organ perfusion during OPCAB of posterior vessels in patients on beta(1)-blockers.