Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Lidocaine plasma levels following two techniques of obturator nerve block.
To assess plasma levels and the potential toxicity of lidocaine following two different approaches to the obtruator nerve. ⋯ Despite a lower total dose of lidocaine administered (450 mg), higher mean and peak plasma levels were reached sooner with bilateral direct obturator nerve block compared with the indirect obturator nerve block (600 mg), indicating a faster blood absorption of lidocaine following direct block. Both types of obturator nerve block prevented adductor muscle contraction in a large percentage of cases.
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Case Reports
Reexpansion pulmonary edema occurring after thoracoscopic drainage of a pleural effusion.
Video assisted thoracoscopic drainage and tale pleurodesis was used to treat a recurrent pleural effusion in a 60 year-old woman undergoing major gynecologic surgery. She developed reexpansion pulmonary edema immediately following surgery. Several important risk factors that were present in this patient are discussed. In addition to almost, complete collapse of the underlying lung for several weeks, thoracoscopy resulted in manipulations and rapid re-inflation of the underlying lung, which further increased the risk to the patient.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
A phase III, multicenter, open-label, randomized, comparative study evaluating the effect of sevoflurane versus isoflurane on the maintenance of anesthesia in adult ASA class I, II, and III inpatients.
To compare the clinical efficacy and safety of sevoflurane and isoflurane when used for the maintenance of anesthesia in adult ASA I, II, and III inpatients undergoing surgical procedures of at least 1 hour's duration. ⋯ Sevoflurane anesthesia, as compared with isoflurane, may be advantageous in providing a smoother clinical course with a more rapid recover.
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Randomized Controlled Trial Comparative Study Clinical Trial
Study of the safe threshold of apneic period in children during anesthesia induction.
(1) To investigate changes in arterial oxygen saturation via pulse oximeter (SpO2) during apnea and after reinstitution of manual ventilation at SpO2 of 95% or 90% following rapid sequence induction of anesthesia in children after 2-minute preoxygenation; (2) to determine whether the setting of a safe threshold of apneic period to an SpO2 of 95% is appropriate in children during anesthetic induction; and (3) to evaluate the influences of age, body weight, and height on the time from the start of apnea to SpO2 of 95%. ⋯ The safe threshold of an apneic period setting to an SpO2 of 95% was appropriate in children during anesthesia induction. Despite the same duration of preoxygenation, younger children were more susceptible than elder ones to the risk of hypoxemia during apnea. The apnea time to SpO2 of 95% correlated with age, body weight, and height using linear regression analysis.
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Comparative Study
Automated ST-segment analysis during cesarean delivery: effects of ECG filtering modality.
To determine the effect of different electrocardiographic (ECG) filtering modalities on ST-segment changes during cesarean delivery. We compared the use of narrow and standard bandwidth ECG filtering modes in assessing ECG-detected ischemic changes in healthy patients undergoing routine, elective cesarean delivery. ⋯ In patients at low risk for myocardial ischemia, narrow bandwidth (monitor mode) ECG filtering reveals greater degrees of ST-segment depression than does standard (diagnostic mode) ECG filtering. Studies examining ST-segment phenomena would be facilitated by including a description of the ECG filtering-technique.