Journal of clinical anesthesia
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Comparative Study Clinical Trial
Intrathecal morphine for postoperative analgesia following repair of frontal encephaloceles in children: comparison with intermittent, on-demand dosing of nalbuphine.
To determine the efficacy of lumbar intrathecal (i.t.) morphine in a dose of 0.02 mg/kg in providing analgesia following repair of frontal encephaloceles. ⋯ Lumbar IT morphine provides effective analgesia following repair of frontal encephaloceles in children and adolescents.
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Randomized Controlled Trial Clinical Trial
Catecholamine and renin-angiotensin response during controlled hypotension induced by prostaglandin E1 combined with hemodilution during isoflurane anesthesia.
To evaluate the catecholamine and renin-angiotensin response during controlled hypotension combined with hemodilution in the clinical setting. ⋯ The combination of hemodilution and PGE1 induced controlled hypotension causes significant responses, especially in a renin-angiotensin-aldosterone system under isoflurane anesthesia.
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To evaluate the influence of major abdominal surgery on the plasma levels of inflammatory cytokines interleukin-6 (IL-6), interleukin-8 (IL-8) and granulocyte colony-stimulating factor (G-CSF). ⋯ These results suggest that major upper abdominal surgery stimulates the release of inflammatory cytokines presumably from the operation site. Further study is warranted to evaluate the modulation of inflammatory responses in the perioperative period.
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To determine how controversial the management of a number of clinical scenarios that are labeled as controversial (eg, how to induce anesthesia in the "open eye-full stomach" patient) are among those practicing anesthesia. ⋯ This survey of anesthesiologists regarding these controversial clinical scenarios showed that (a) most scenarios were in fact controversial amongst those in practice, and (b) there were disparities between whether a technique is believed to be acceptable practice and whether it would be used in one's own practice.
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Case Reports Clinical Trial
Hemodynamic changes during laparoscopic cholecystectomy in patients with severe cardiac disease.
To evaluate the hemodynamic changes and need for pharmacologic interventions during laparoscopic cholecystectomy in patients with severe cardiac dysfunction. ⋯ Laparoscopic cholecystectomy in patients with severe cardiac dysfunction results in significant hemodynamic changes.