Journal of clinical anesthesia
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Randomized Controlled Trial
The influence of timing of systemic ketamine administration on postoperative morphine consumption.
To determine the influence of timing of systemic ketamine administration on postoperative morphine consumption. ⋯ Lower pain scores and morphine consumption in groups 2 and 3 may be related to higher plasma ketamine concentrations caused by the higher doses and later administration. Our findings suggest that a single preoperative dose of ketamine provided less analgesia compared with other dosing regimens that included intraoperative infusions or postoperative administration.
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Clinical Trial
Effects of morphine and its metabolites on immune function in advanced cancer patients.
To determine whether morphine and its active metabolites such as morphine-3-glucuronide (M-3-G) and morphine-6-glucuronide (M-6-G) modulate immune function in patients with advanced cancer who required morphine for pain relief. ⋯ The present study suggests that some of humoral and cellular immunity are modulated by morphine-derived metabolites at the early phase of morphine therapy in patients with advanced cancer.
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We describe the anesthetic management difficulties of a man with mucopolysaccharidosis I. We also briefly review the anesthesia literature related to this disease.
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Case Reports
Apparent sialadenopathy of the sublingual glands after general anesthesia with placement of laryngeal mask airway.
Sialadenopathy, inflammation of the salivary glands, is a rare anesthetic complication. This case conference describes a patient who developed sialadenopathy of the sublingual glands after placement of a laryngeal mask airway during a brief surgical procedure. The patient's history is detailed, the surgical and anesthetic procedures are described, and a discussion follows, which describes the different causes of this inflammatory process. In the comment, the physiology of the salivary gland is described in detail.
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To describe our systematic approach to securing the airway in patients with laryngeal tumors, developed over a 10-year period. ⋯ With these guidelines, we have reduced the frequency of emergencies because of a lost airway, bleeding, or dislodging of tumor.