Journal of clinical anesthesia
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Observational Study
External validation of a predictive model for reintubation after cardiac surgery: A retrospective, observational study.
Explore validation of a model to predict patients' risk of failing extubation, to help providers make informed, data-driven decisions regarding the optimal timing of extubation. ⋯ Future work is needed to explore how to optimize models before local implementation.
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Observational Study
Caffeine administration to treat oversedation after general anesthesia: A retrospective analysis.
Our institution has adopted an informal practice of administering postoperative caffeine to expedite anesthesia recovery for patients with excessive sedation. This study aimed to determine whether caffeine administration was associated with improved sedation recovery and reduced risk of respiratory complications. ⋯ In this observational study, caffeine administration during anesthesia recovery was associated with improved sedation scores. However, it was also associated with an increased risk of respiratory complications, possibly reflecting selection bias (ie, administering caffeine to higher-risk patients). Patients with signs of excessive sedation during anesthesia recovery may benefit from enhanced postoperative respiratory monitoring.
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Comment Letter Randomized Controlled Trial
Comment on: Vitamin C and catheter-related bladder discomfort after transurethral resection of bladder tumor: A double-blind, randomized, placebo-controlled study.
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To evaluate the association between midazolam premedication and postoperative delirium in a large retrospective cohort of patients ≥70 years. ⋯ Our results suggest that low doses of midazolam can be safely used to pre-medicate elective surgical patients 70 years or older before non-cardiac surgery, without significant effect on the risk of developing postoperative delirium.