Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Changes in respiratory pattern and arterial blood gases during sedation with propofol or midazolam in spinal anesthesia.
To investigate changes in respiratory pattern and arterial blood gases during sedation with propofol or midazolam in spinal anesthesia. ⋯ Significant decreases in %RC and pO2 during propofol sedation seem to depend on paradoxical respiration due, in part, to upper airway obstruction; therefore, attention should be directed to the respiratory pattern during sedation, especially with propofol.
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To determine the influences of age and gender on the dose response and the time course of effect of atracurium. ⋯ Age and gender have significant effects on the dose response and time course of effect of atracurium. Older patients and women are more sensitive to atracurium-induced neuromuscular block than are young patients and men.
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Randomized Controlled Trial Comparative Study Clinical Trial
Abdominal wall lift versus carbon dioxide insufflation for laparoscopic resection of ovarian tumors.
To evaluate and compare changes in pulmonary mechanics and stress hormone responses between abdominal wall lift (gasless) and carbon dioxide (CO2) insufflation laparoscopic surgery during controlled general anesthesia. ⋯ Abdominal wall lift laparoscopic surgery is physiologically superior to CO2 pneumoperitoneum laparoscopic surgery as seen during the conditions of this study. Abdominal wall lift laparoscopic surgery provides normal acid-base balance and a lesser degree of hormonal stress responses, it maintains urine output, and it avoids derangement of pulmonary mechanics.
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Randomized Controlled Trial Clinical Trial
Interaction modeling of propofol and sufentanil on loss of consciousness.
To examine the possible pharmacodynamic interaction of propofol and sufentanil with respect to the induction of loss of consciousness. ⋯ Our results give no evidence of additional hypnotic properties of sufentanil compared to the other fentanyl congeners, although logistic regression may be of limited value in modeling interaction of hypnotic-analgesic combinations.