Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Effects of intravenous and oral clonidine on hemodynamic and plasma-catecholamine response due to endotracheal intubation.
To investigate the effects of intravenous (IV) versus oral clonidine on alterations of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and plasma-catecholamines due to endotracheal intubation. ⋯ In conclusion, IV clonidine reduced stress response to endotracheal intubation compared with placebo. Oral clonidine at the dose used was less effective in blunting hemodynamic stress response than IV clonidine.
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Comparative Study Clinical Trial
A comparison of propofol and remifentanil during monitored anesthesia care.
To compare remifentanil, an esterase-metabolized opioid, to a standard propofol-based sedation technique for monitored anesthesia care (MAC). ⋯ Remifentanil provided comparable intraoperative conditions and patient comfort at a lower sedation level compared with propofol. However, remifentanil was associated with greater respiratory depression and a longer time to home readiness.
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Comparative Study Clinical Trial
Pipecuronium revisited: dose-response and maintenance requirement in infants, children, and adults.
To compare dose-response relationship and maintenance requirement of pipecuronium in anesthetized infants, children, and adults. ⋯ Bolus dose requirement of pipecuronium is greatest in children. Maintenance requirement is related to potency in each age group studied.
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To survey cost containment activities in anesthesiology and to determine to what extent departments use cost policies and guidelines. ⋯ Anesthesiology departments are experiencing pressure to reduce costs and the majority have cost policies and guidelines concerning utilization of ORs and anesthetic drugs. Academic anesthesiology departments may be experiencing more cost-containment pressure than nonacademic departments.