Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Study of the safe threshold of apneic period in children during anesthesia induction.
(1) To investigate changes in arterial oxygen saturation via pulse oximeter (SpO2) during apnea and after reinstitution of manual ventilation at SpO2 of 95% or 90% following rapid sequence induction of anesthesia in children after 2-minute preoxygenation; (2) to determine whether the setting of a safe threshold of apneic period to an SpO2 of 95% is appropriate in children during anesthetic induction; and (3) to evaluate the influences of age, body weight, and height on the time from the start of apnea to SpO2 of 95%. ⋯ The safe threshold of an apneic period setting to an SpO2 of 95% was appropriate in children during anesthesia induction. Despite the same duration of preoxygenation, younger children were more susceptible than elder ones to the risk of hypoxemia during apnea. The apnea time to SpO2 of 95% correlated with age, body weight, and height using linear regression analysis.
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Randomized Controlled Trial Comparative Study Clinical Trial
Preventing pain during injection of propofol: the optimal dose of lidocaine.
To define the optimal dose of lidocaine to be added to propofol to reduce the incidence of pain during its injection. ⋯ Within this dose range and in this patient population, 30 mg of lidocaine is optimal for reducing the pain during injection of propofol.
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Randomized Controlled Trial Comparative Study Clinical Trial
Lidocaine plasma levels following two techniques of obturator nerve block.
To assess plasma levels and the potential toxicity of lidocaine following two different approaches to the obtruator nerve. ⋯ Despite a lower total dose of lidocaine administered (450 mg), higher mean and peak plasma levels were reached sooner with bilateral direct obturator nerve block compared with the indirect obturator nerve block (600 mg), indicating a faster blood absorption of lidocaine following direct block. Both types of obturator nerve block prevented adductor muscle contraction in a large percentage of cases.
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To test the hypothesis that morbid obesity implies increased difficulty of liver transplantation and increased risk of adverse outcome. ⋯ Morbid obesity alone does not predispose to increased complications or decreased survival after liver transplantation.
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Comparative Study
Automated ST-segment analysis during cesarean delivery: effects of ECG filtering modality.
To determine the effect of different electrocardiographic (ECG) filtering modalities on ST-segment changes during cesarean delivery. We compared the use of narrow and standard bandwidth ECG filtering modes in assessing ECG-detected ischemic changes in healthy patients undergoing routine, elective cesarean delivery. ⋯ In patients at low risk for myocardial ischemia, narrow bandwidth (monitor mode) ECG filtering reveals greater degrees of ST-segment depression than does standard (diagnostic mode) ECG filtering. Studies examining ST-segment phenomena would be facilitated by including a description of the ECG filtering-technique.