Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Efficacy and safety of divided dose administration of mivacurium for a 90-second tracheal intubation.
To compare the safety and effectiveness of 0.25 mg divided doses of mivacurium chloride to succinylcholine for a 90-second tracheal intubation. ⋯ When Sch is not desirable, mivacurium 0.25 mg/kg given as a divided dose provides good to excellent intubation conditions 90 seconds after the initial dose without significant changes in MAP or HR. It can be an appropriate alternative for short surgical procedures. It must be emphasized that this conclusion does not apply to rapid-sequence induction-intubation.
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Randomized Controlled Trial Comparative Study Clinical Trial
Incidence of nausea and vomiting in outpatients undergoing general anesthesia in relation to selection of intraoperative opioid.
To measure the incidence of nausea and vomiting in outpatients in relation to selection of, or withholding of, intraoperative opioid. ⋯ Opioid administration at the doses employed during induction of anesthesia does not promote postoperative nausea or vomiting, nor increase length of stay in the PACU.
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Randomized Controlled Trial Clinical Trial
Oxygen administration during transport and recovery after outpatient surgery does not prevent episodic arterial desaturation.
To compare the efficacy of two different oxygen (O2) delivery systems in preventing episodic arterial desaturation in the immediate postoperative period. ⋯ Routine O2 administration during transport and PACU stay did not abolish episodic desaturation, even in healthy patients undergoing minor surgical procedures. Given the marked difference in acquisition cost, it would appear that O2 administration by nasal cannula is a more cost-effective alternative for routine postoperative O2 administration in certain groups of patients undergoing general anesthesia for outpatient surgery.
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To identify the frequency, outcome, and factors associated with unplanned endotracheal extubation (UE) in the intensive care unit (ICU). ⋯ Patients should be observed closely after unplanned extubation, although many may not require reintubation. Reintubation can be quite difficult, necessitating highly skilled airway management. Attention to associated risk factors may decrease the incidence of both accidental and self-extubation.
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To determine whether propofol emulsion, fentanyl, and vecuronium remain compatible and stable when mixed in clinically appropriate concentrations. ⋯ The propofol, fentanyl, and vecuronium mixtures studied were compatible and stable immediately after mixing. Appropriate in vitro compatibility testing is recommended before clinical evaluation of propofol-opioid or propofol-opioid-muscle relaxant mixtures.