Journal of clinical anesthesia
The most recent articles from:
J Clin Anesth
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Randomized Controlled Trial Comparative Study Clinical Trial
Pharmacokinetics of intranasal alfentanil.
To determine the pharmacokinetics of intranasal and intravenous (IV) administrations of alfentanil in 10 healthy volunteers. ⋯ This pharmacokinetic study demonstrates a rapid rise in plasma concentrations, as well as a high bioavailability, following the intranasal administration of alfentanil.
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Randomized Controlled Trial Clinical Trial
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
To investigate the efficacy, opioid-sparing effects and any reduction in adverse events of a continuous intravenous (i.v.) infusion of ketorolac following lower abdominal surgery. ⋯ Intravenous infusion of ketorolac combined with morphine delivered via a PCA device would appear to be a valuable method of providing balanced analgesia following lower abdominal surgery.