Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
The effect of ondansetron on atracurium-induced neuromuscular blockade.
To determine whether treatment with ondansetron, a new antiemetic drug, affects nondepolarizing neuromuscular blockade. ⋯ Ondansetron is an antiemetic drug that can be used in the perioperative period without concern for potentiation of nondepolarizing neuromuscular blockade, change in atracurium maintenance dose, or change in rate of neostigmine-induced recovery from neuromuscular blockade with atracurium.
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Randomized Controlled Trial Clinical Trial
Fenoldopam infusion for the treatment of postoperative hypertension.
To examine the safety and efficacy of intravenous fenoldopam as compared to placebo for the treatment of postoperative hypertension. ⋯ Fenoldopam is an effective drug for reducing BP following hypertensive episodes in the postoperative setting. Fenoldopam use is associated with an increase in HR versus placebo.
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To investigate the effect of intravenous (IV) phenylephrine (PHE) bolus administration on left ventricular function in patients who developed postural hypotension during isoflurane anesthesia in the head-up tilt (reverse Trendelenburg) position. ⋯ PHE bolus administration effectively restored BP and cardiac filling, which were reduced after head-up tilt, without causing a relevant impairment of left ventricular function or an increase in end-systolic wall stress above the upper normal limit.
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Randomized Controlled Trial Comparative Study Clinical Trial
Propofol versus midazolam for monitored sedation: a comparison of intraoperative and recovery parameters.
To compare intraoperative and recovery parameters in patients who received either propofol infusion (PI), propofol bolus (PB), or midazolam bolus (MZ) for sedation. ⋯ The PI, PB, and MZ groups all gave excellent sedation for patients undergoing surgical procedures with local anesthesia. Amnesia was greatest with midazolam, and recovery was more rapid with propofol.