Journal of clinical anesthesia
-
Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of fentanyl-propofol with a ketamine-propofol combination for sedation during endometrial biopsy.
The purpose of this study was to compare the clinical activities of ketamine and fentanyl when used in combination with propofol for outpatients undergoing endometrial biopsy. The investigated parameters were respiration, sedation, recovery rate, side effects, time to discharge, and patient satisfaction. ⋯ Hemodynamic change and degrees of sedation showed that fentanyl-propofol and ketamine-fentanyl combinations can be used safely in patients undergoing endometrial biopsy. However, with regard to side effects and patient satisfaction, the fentanyl-propofol was superior.
-
Randomized Controlled Trial Clinical Trial
Reduction of postoperative emetic episodes and analgesic requirements with dexamethasone in patients scheduled for dental surgery.
To evaluate the antiemetic and analgesic effects of dexamethasone for the first 24 hours postoperatively in patients scheduled for dental surgery. ⋯ Prophylactic dexamethasone 8 mg is effective for the prevention of nausea and vomiting after dental surgery and in the management of postoperative pain. Increasing the dose to 16 mg provides no further benefit.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Bupivacaine versus L-bupivacaine for labor analgesia via combined spinal-epidural: a randomized, double-blinded study.
To compare the intensity and duration of motor block and the duration of sensory block with racemic bupivacaine and l-bupivacaine for combined spinal-epidural analgesia, as previous studies have shown contradictory results. ⋯ Contrary to earlier studies, we did not find any difference in the intensity and duration of sensory or motor blocks between racemic bupivacaine and l-bupivacaine. Based on our findings in the parturient population studied, we conclude that l-bupivacaine does not offer any advantages over racemic bupivacaine when used for combined spinal-epidural for labor analgesia.
-
Randomized Controlled Trial Clinical Trial
Effect of different anesthesia techniques on red blood cell endogenous recovery in hip arthroplasty.
To compare the magnitude of postoperative red blood cell (RBC) recovery with 3 different anesthetic techniques, general anesthesia (GA), epidural anesthesia (EA) alone, and the combination of these 2 techniques (CA), in patients undergoing total hip arthroplasty. ⋯ Patients who had received EA had a faster recovery of the circulating erythrocyte mass than those who had had GA or CA. The presence of nitrous oxide in the anesthetic gas mixture might inhibit erythropoiesis by altering vitamin B(12) functions.
-
Randomized Controlled Trial Clinical Trial
The combination of epidural clonidine and S(+)-ketamine did not enhance analgesic efficacy beyond that for each individual drug in adult orthopedic surgery.
To evaluate the benefit of epidural clonidine and S(+)-ketamine combination through the epidural route in adult orthopedic surgery. ⋯ The association of epidural clonidine or S(+)-ketamine did not result in a greater analgesic effect in the model of acute postoperative pain studied, although the interaction of epidural clonidine and S(+)-ketamine is not attributable to sharing of a common second messenger system.