Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Comparison of ropivacaine-fentanyl patient-controlled epidural analgesia with morphine intravenous patient-controlled analgesia for perioperative analgesia and recovery after open colon surgery.
To compare the effects of ropivacaine-fentanyl patient-controlled epidural analgesia (PCEA) with morphine intravenous (IV) patient-controlled analgesia (PCA). ⋯ Ropivacaine-fentanyl PCEA provides superior analgesia, reduced opioid requirement, and more rapid recovery after colon surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effect of laryngeal mask airway on esophageal motility during general anesthesia.
To determine whether the Laryngeal Mask Airway (LMA) triggers the pharyngo-esophago-gastric reflex during general anesthesia by comparing the esophageal motility of patients with the LMA and endotracheal tube (ETT) in place. ⋯ During the general anesthetic period before the arousal phase in this study, a LMA does not provoke significantly different esophageal peristalsis compared with an ETT. Thus, the LMA is unlikely to stimulate the pharyngo-esophago-gastric reflex during that period.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
A comparison of the remifentanil and fentanyl adverse effect profile in a multicenter phase IV study.
To compare the frequency of adverse effects of remifentanil and fentanyl in a large and diverse patient population. ⋯ In the doses used, both remifentanil and fentanyl have a similar frequency of adverse effects except for the higher frequency of hypotension associated with the use of remifentanil.
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Randomized Controlled Trial Clinical Trial
Effect of maintenance bolus on the recovery profile of a short-acting nondepolarizing muscle relaxant.
To evaluate the effect of different maintenance boluses of a short-acting nondepolarizing neuromuscular blocking drug on its spontaneous recovery profile during anesthesia. ⋯ Spontaneous recovery of the T(1) to 25% of the baseline value occurred 6 to 10 minutes after a maintenance bolus dose of rapacuronium 0.25 to 0.75 mg x kg(-1) i.v. However, recovery to a TOF>0.7 required 44 to 66 minutes during desflurane anesthesia.
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Randomized Controlled Trial Clinical Trial
Patient-controlled bupivacaine wound instillation following cesarean section: the lack of efficacy of adjuvant ketamine.
To assess the analgesic efficacy of ketamine when administered as an adjuvant to bupivacaine for patient-controlled wound instillation following cesarean section. ⋯ Adjuvant local ketamine does not enhance bupivacaine-induced wound instillation following cesarean section.