Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Individualized outcome feedback produces voluntary antiemetic prescribing practice changes.
To determine the impact of individualized outcome feedback on antiemetic prescribing practices and compare outcomes of a cost-effective, standardized antiemetic protocol (PROT) to that of customized antiemetic therapy (NONPROT). ⋯ Individualized outcome feedback produced a 48% reduction in monthly expenditures for ondansetron and droperidol, which was sustained after the study. Patients satisfaction between ondansetron 4 mg and droperidol 0.625 mg given in the PACU did not differ in spite of a slightly greater efficacy of ondansetron as a first-line drug.
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Randomized Controlled Trial Clinical Trial
The effect of repeated epidural sympathetic nerve block on "failed back surgery syndrome" associated chronic low back pain.
To assess the therapeutic benefits of repeated epidural local anesthetic administration on pain perception and straight leg raise (SLR) in patients suffering from chronic low back pain. ⋯ 46 patients completed the study. VAS for pain was marginally lower in Group B. However, statistical significance was not demonstrated. During the hospitalization period, the SLR in both study groups significantly (0.008) improved with time. However, no difference between the groups was demonstrated. In both groups, 1 week, 1 month, and 3 months after discharge, the SLR was comparable to prestudy recordings. In Group B, at 1 week, 1 month, and 3 months after discharge, patient-generated VAS for pain were significantly (p = 0.002) higher when compared to pain scores at the time of patient discharge.
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Randomized Controlled Trial Clinical Trial
The effect of propofol and thiamylal on hypertensive responses to a rapid increase in isoflurane concentration.
To compare the effects of propofol and thiamylal on the hyperdynamic circulatory response caused by a rapid increase in isoflurane concentration. ⋯ Propofol induction of anesthesia more effectively attenuates the circulatory responses to a sudden increase in isoflurane concentration than does thiamylal.
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Randomized Controlled Trial Comparative Study Clinical Trial
The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia.
To investigate the effects of preanesthetic oral clonidine on total propofol requirement for uniform minor surgery (breast conservative surgery: breast cancer removal with axillary lymph node dissection), and to compare the action of clonidine with that of preanesthetic oral diazepam, a commonly used benzodiazepine. ⋯ Preanesthetic oral clonidine (150 micrograms) but not diazepam (10 mg) reduced the total requirement of propofol while stabilizing hemodynamic parameters. In addition, 150 micrograms of oral clonidine attenuates the hemodynamic responses associated with tracheal intubation.
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Randomized Controlled Trial Comparative Study Clinical Trial
The induction, maintenance, and recovery characteristics of spinal versus general anesthesia in elderly patients.
To compare the induction and recovery profiles of three combinations of general anesthesia when used as an alternative to spinal anesthesia for elderly patients. ⋯ General anesthesia with propofol and desflurane facilitates shorter induction and recovery times without adversely affecting patient comfort. Therefore, this technique may be preferable to spinal anesthesia for elderly patients undergoing short transurethral surgical procedures.