Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Renal function in patients during and after hypotensive anesthesia with sevoflurane.
To evaluate renal function during and after hypotensive anesthesia with sevoflurane compared with isoflurane in the clinical setting. ⋯ Two hours of hypotensive anesthesia with sevoflurane under 5 L/min total gas flow in patients having no preoperative renal dysfunction transiently increased NAG, which is consistent with a temporary, reversible disturbance of renal tubular function.
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Randomized Controlled Trial Clinical Trial
Consideration of the optimal epidural fentanyl doses in abdominal surgery.
To determine an optimal dose of epidural fentanyl in open abdominal surgery by examining the effects of different doses of epidural fentanyl in combination with or without low concentration of lidocaine on hemodynamic and endocrine responses to surgical stress. ⋯ Epidural fentanyl 3 micrograms/kg with 0.5% lidocaine may be most adequate for laparotomy because these doses caused neither bradycardia nor increments of norepinephrine perioperatively.
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Randomized Controlled Trial Clinical Trial
Oral clonidine premedication does not prolong analgesia after herniorrhaphy under subarachnoid anesthesia.
To determine the effect of oral clonidine premedication on duration of sensory and motor block, postoperative analgesia, hemodynamic stability, sedation, and respiratory parameters after subarachnoid anesthesia (SA). ⋯ In healthy patients, premedication with oral clonidine provided useful sedation and anxiolysis and stable hemodynamics, without prolongation of sensory and motor block. Side effects occurred only with clonidine 5 mcg/kg. Thus, a dose of 2.5 mcg/kg is recommended.
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Randomized Controlled Trial Clinical Trial
Alfentanil decreases the excitatory phenomena of sodium methohexital.
To evaluate the effects of alfentanil or lidocaine on the excitatory phenomena (myoclonus, cough, hiccough) caused by methohexital anesthesia and on the hemodynamic changes induced by retrobulbar block. ⋯ A small dose of alfentanil (5 micrograms/kg i.v.) decreases myoclonus and cough induced by sodium methohexital anesthesia i.v., resulting in improved quality of induction of anesthesia. Alfentanil also attenuates the cardiovascular responses caused by placement of a retrobulbar block.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of three different doses of intrathecal fentanyl and sufentanil for labor analgesia.
To compare the duration of analgesia and incidence of side effects of three doses of intrathecal fentanyl (25 micrograms, 37.5 micrograms, 50 micrograms) with three doses of intrathecal sufentanil (5 micrograms, 10 micrograms, 15 micrograms). ⋯ Intrathecal sufentanil produced analgesia of longer duration than fentanyl for all doses studied. The duration of pruritus with sufentanil was also longer.