Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Catecholamine and renin-angiotensin response during controlled hypotension induced by prostaglandin E1 combined with hemodilution during isoflurane anesthesia.
To evaluate the catecholamine and renin-angiotensin response during controlled hypotension combined with hemodilution in the clinical setting. ⋯ The combination of hemodilution and PGE1 induced controlled hypotension causes significant responses, especially in a renin-angiotensin-aldosterone system under isoflurane anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
Priming with rocuronium accelerates the onset of neuromuscular blockade.
To investigate the effects of priming rocuronium on the time course of neuromuscular blockade. ⋯ Priming rocuronium decreased the onset times and thus, the intubating times without increasing the clinical duration of action or recovery index.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postoperative analgesia with parenteral opioids: does continuous delivery utilizing a transdermal opioid preparation affect analgesic efficacy or patient safety?
To compare, in patients who underwent major orthopedic surgical procedures, the efficacy of intravenous (IV) patient-controlled analgesia (PCA) with morphine combined with continuous administration of two doses of fentanyl or placebo via transdermal therapeutic system with fentanyl (TTSF) patches. ⋯ There is no significant advantage to the routine use of continuous transdermal opioid delivery in patients receiving IV PCA after major orthopedic surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postthyroidectomy analgesia: morphine, buprenorphine, or bupivacaine?
To compare three analgesic regimens for pain relief after thyroidectomy. ⋯ The administration of sublingual buprenorphine after thyroidectomy provides better analgesia than small doses of oral controlled-release morphine or than 0.25% bupivacaine wound infiltration at the end of surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of general anesthesia with and without lumbar epidural for total hip arthroplasty: effects of epidural block on hip arthroplasty.
To determine whether lumbar epidural anesthesia, when combined with general anesthesia, decreases perioperative blood loss, the incidence of postoperative deep vein thrombosis (DVT), cardiac dysrhythmias, and ischemia in patients undergoing total hip arthroplasty (THA). ⋯ Combined regional-general anesthesia decreases intraoperative blood loss in THA, and thereby offers an advantage over general anesthesia alone.