Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Cardiovascular stability during carotid endarterectomy: endotracheal intubation versus laryngeal mask airway.
To compare cardiovascular stability during carotid endarterectomy in groups managed either with laryngeal mask airway (LMA) or endotracheal intubation. ⋯ During carotid endarterectomy, a reduced incidence of hypertensive and tachycardic episodes, as well as such episodes requiring interventional drug therapy, was found in the group whose airway is managed by LMA when compared with endotracheal intubation.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparative effects of Ringer's acetate and lactate solutions on intraoperative central and peripheral temperatures.
To compare the effects of Ringer's lactate (LR) and Ringer's acetate (AR) solutions on core body and peripheral temperatures during isoflurane or sevoflurane anesthesia. ⋯ There was no significant difference between AR and LR in the preservation of heat during either sevoflurane or isoflurane anesthesia. However, AR may be superior to LR for maintaining central temperature during the early period of isoflurane anesthesia.
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Randomized Controlled Trial Clinical Trial
Ondansetron dose response curve in high-risk pediatric patients.
To establish a dose-response relationship for ondansetron, and to evaluate any effects of oral premedication with metoclopramide in pediatric patients undergoing tonsillectomy and adenoidectomy and strabismus surgery. ⋯ Ondansetron is an effective medication for the treatment and prevention of postoperative nausea and vomiting, and a dose of ondansetron 0.05 mg/kg is as effective as 0.1 mg/kg and 0.15 mg/kg. Metoclopramide 0.15 mg/kg has no effect on the incidence of postoperative nausea and vomiting.
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Randomized Controlled Trial Clinical Trial
Combined hemodilution and hypotension monitored with jugular bulb oxygen saturation, EEG, and ECG decreases transfusion volume and length of ICU stay for major orthopedic surgery.
To assess the efficacy and safety of hemodilution combined with induced hypotension during surgery. ⋯ Hemodilution combined with induced hypotension was safe and may reduce the need for transfusion and ICU admission.
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Randomized Controlled Trial Multicenter Study Clinical Trial
A double-blind, parallel-group, placebo-controlled, dose-ranging, multicenter study of intravenous granisetron in the treatment of postoperative nausea and vomiting in patients undergoing surgery with general anesthesia.
To compare the effectiveness of granisetron with placebo in the treatment of established postoperative nausea and vomiting (PONV). ⋯ Granisetron was significantly more effective than placebo in all groups. Further studies in specific subgroups may be warranted.