Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Pharmacokinetics of intranasal alfentanil.
To determine the pharmacokinetics of intranasal and intravenous (IV) administrations of alfentanil in 10 healthy volunteers. ⋯ This pharmacokinetic study demonstrates a rapid rise in plasma concentrations, as well as a high bioavailability, following the intranasal administration of alfentanil.
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Randomized Controlled Trial Clinical Trial
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
To investigate the efficacy, opioid-sparing effects and any reduction in adverse events of a continuous intravenous (i.v.) infusion of ketorolac following lower abdominal surgery. ⋯ Intravenous infusion of ketorolac combined with morphine delivered via a PCA device would appear to be a valuable method of providing balanced analgesia following lower abdominal surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Study of the optimal duration of preoxygenation in children.
To determine the optimal length of preoxygenation in children. ⋯ 2 minutes of preoxygenation in children can provide the maximum benefit of denitrogenation and achieve 2 minutes of safe apea. 95% and 99% confidence intervals were 69 to 100 and 59 to 100, respectively. Succinylcholine had only a slight effect on the safe apneic period.
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Randomized Controlled Trial Comparative Study Clinical Trial
Laryngeal mask airway: a more successful method of insertion.
To compare the ease of insertion of the laryngeal mask airway (LMA) by two methods. ⋯ Inserting the LMA with the cuff partially inflated is likely to be more successful than with the cuff fully deflated. When it is not possible to insert the LMA with the cuff fully deflated, partial inflation before insertion may result in correct placement.
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Randomized Controlled Trial Clinical Trial
Alfentanil suppresses coughing and agitation during emergence from isoflurane anesthesia.
To evaluate the effectiveness of alfentanil in suppressing coughing and agitation during emergence from isoflurane anesthesia. ⋯ Alfentanil decreased coughing, agitation, and cardiovascular stimulation during emergence from isoflurane anesthesia without prolonging the time of extubation.