Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of dexmedetomidine and midazolam sedation and antagonism of dexmedetomidine with atipamezole.
To evaluate the effects of dexmedetomidine, an alpha-2 agonist, as an intravenous sedative drug and the effects of atipamezole, an alpha-2 antagonist, on recovery. ⋯ Atipamezole is an effective antagonist for reversing psychomotor impairment following dexmedetomidine sedation.
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Randomized Controlled Trial Clinical Trial
Intravenous clonidine fails to reduce postoperative meperidine requirements.
To investigate the effect of an additional postoperative intravenous (IV) clonidine infusion on meperidine requirements in the early postoperative period. ⋯ During the first 2 postoperative hours following cholecystectomy, postoperative meperidine intake could not be reduced by IV administration of clonidine 300 micrograms.
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Randomized Controlled Trial Clinical Trial
Role of the laryngeal mask airway in the immobile cervical spine.
To determine whether the laryngeal mask airway has a useful role in the airway management of patients whose cervical spines are immobilized in a rigid cervical collar. ⋯ The laryngeal mask airway compared favorably with an endotracheal tube in success rate, difficulty of insertion, and time to position correctly in this patient population. Although the laryngeal mask does not reliably protect against aspiration, we believe it may play a useful role if more conventional methods of airway management fail. Further studies in the trauma scenario are indicated.
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Randomized Controlled Trial Clinical Trial
Improved postoperative analgesia with morphine added to axillary block solution.
To determine whether the addition of morphine to the axillary block local anesthetic solution provides improved or prolonged postoperative analgesia. ⋯ The addition of morphine 0.1 mg/kg to the local anesthetic axillary block solution provided improved postoperative analgesia without an increased frequency of side effects or major complications.
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Randomized Controlled Trial Clinical Trial
Interpleural analgesia with bupivacaine following thoracotomy: ineffective results of a controlled study and pharmacokinetics.
To evaluate intrapleural analgesia with bupivacaine following partial pulmonary resection and to determine pharmacokinetic parameters of bupivacaine with epinephrine. ⋯ Intrapleural analgesia conducted with 40 ml of 0.25% bupivacaine with epinephrine or 20 ml of 0.5% bupivacaine with epinephrine was insufficient for pain, despite high plasma bupivacaine concentration.