Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Effect of preanesthetic intramuscular ranitidine on gastric acidity and volume in children.
To evaluate the effects of preanesthetic administration of intramuscular (IM) ranitidine on pH and volume of gastric contents in children. ⋯ Preanesthetic IM ranitidine 1 to 2 mg/kg resulted in a higher pH and lower volume of gastric fluid at the time of induction and in a higher pH during 3 hours of anesthesia. This therapy may be a useful adjunct to premedication for children who have a greater than normal risk of pulmonary aspiration during anesthesia.
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Randomized Controlled Trial Clinical Trial
Maternal and neonatal effects of adding epidural sufentanil to 0.5% bupivacaine for cesarean delivery.
To determine the maternal and fetal effects of the addition of epidural sufentanil to 0.5% bupivacaine for cesarean delivery. ⋯ The epidural injection of sufentanil added to 0.5% bupivacaine with epinephrine improved the quality of anesthesia during elective cesarean section without jeopardizing the safety of the baby.
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Randomized Controlled Trial Clinical Trial
Midazolam potentiates thiopental sodium anesthetic induction in patients.
To test the hypothesis that midazolam potentiates thiopental sodium-induced unconsciousness. ⋯ A subhypnotic dose of midazolam potentiates thiopental sodium-induced unconsciousness. This effect suggests the possibility that midazolam enhances barbiturate binding.
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Randomized Controlled Trial Comparative Study Clinical Trial
The differential cost of anesthesia and recovery with propofol-nitrous oxide anesthesia versus thiopental sodium-isoflurane-nitrous oxide anesthesia.
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Randomized Controlled Trial Clinical Trial
The effects of thiopental sodium on fentanyl-induced muscle rigidity in a human model.
To describe a safe human model in which to study the treatment of fentanyl-induced muscle rigidity and report on the efficacy of thiopental sodium for this purpose. ⋯ Thiopental sodium does blunt the degree of muscle rigidity induced by high-dose fentanyl, though not as effectively as does succinylcholine. One can safely isolate an extremity prior to the administration of high-dose fentanyl and a muscle relaxant, intubate the trachea, and ventilate a patient, while retaining the ability to study the effect of centrally acting drugs on fentanyl-induced rigidity in the isolated extremity.