Journal of clinical anesthesia
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We report two cases of overdoses of intramuscular midazolam used as a premedication. Both cases had no resedation or complications, but the accidents happened as a result of a resident and nurse's lack of experience with midazolam. The intramuscular doses, given at four times the normal quantity, fortunately caused no harm in our cases. However, the situations suggest that we should carefully check the dosage and review the correct procedures, even when using a drug that is considered to be familiar with most practitioners.
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To evaluate whether preoperative blood volume and postoperative blood loss influence blood transfusion in females and males undergoing coronary artery bypass graft (CABG) surgery. ⋯ The greater need for blood transfusion in females than in males during CABG is primarily attributable to significantly lower preoperative total blood volume and RBC volume in females.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
A comparison of the remifentanil and fentanyl adverse effect profile in a multicenter phase IV study.
To compare the frequency of adverse effects of remifentanil and fentanyl in a large and diverse patient population. ⋯ In the doses used, both remifentanil and fentanyl have a similar frequency of adverse effects except for the higher frequency of hypotension associated with the use of remifentanil.
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Randomized Controlled Trial Clinical Trial
Patient-controlled bupivacaine wound instillation following cesarean section: the lack of efficacy of adjuvant ketamine.
To assess the analgesic efficacy of ketamine when administered as an adjuvant to bupivacaine for patient-controlled wound instillation following cesarean section. ⋯ Adjuvant local ketamine does not enhance bupivacaine-induced wound instillation following cesarean section.